11 research outputs found

    Global-mindedness Through the Eyes of EFL Learners: Gender and Level of Proficiency in Focus

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    The major aim of the present study is to find connections between global-mindedness and some important factors such as gender and level of proficiency. To this end, 182 language learners, 92 females and 90 males, participated in the study. These students were selected and categorized based on one-stage cluster sampling from 16 branches of different language centers, namely Safiran, Shoukoh, and Kish. The main phase of the study was conducted through the use of Google Docs platform that provides the researchers with the well-organized data. Language learners were asked to answer all the demographic information by considering their anonymity during the process of data collection. The result of the study, through t-test, showed that there was a significant difference between male and female language learners regarding their level of global-mindedness. The result also showed that the level of proficiency of the female language learners does not influence their level of global-mindedness.Мета дослідження полягає в знаходженні зв'язку між глобальним мисленням і деякими важливими чинниками, як-от стать і рівень майстерності. У дослідженні взяло участь 182 особи, з яких 92 особи жіночої статі та 90 осіб чоловічої статі. Студенти були відібрані і поділені на групи за принципом одноступінчастого кластеру з вибіркою 16-ти філіалів різних мовних центрів, а саме «Сафіран», «Шоуко», і «Кіш». Основний етап дослідження було проведено за допомогою використання сервісу Google Docs, що забезпечує дослідників добре впорядкованими даними. Студентам було запропоновано надати повну демографічну інформацію про себе зі збереженням принципу анонімності протягом процесу збору даних. Результати Т-тесту (t-критерій Стьюдента) показали велику різницю глобального мислення між мовою осіб чоловічої і жіночої статі. Серед студентів жіночої статі вагомої різниці між глобальним мисленням і рівнем володіння мовою не було виявлено

    Managed Geo-Distributed Feature Store: Architecture and System Design

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    Companies are using machine learning to solve real-world problems and are developing hundreds to thousands of features in the process. They are building feature engineering pipelines as part of MLOps life cycle to transform data from various data sources and materialize the same for future consumption. Without feature stores, different teams across various business groups would maintain the above process independently, which can lead to conflicting and duplicated features in the system. Data scientists find it hard to search for and reuse existing features and it is painful to maintain version control. Furthermore, feature correctness violations related to online (inferencing) - offline (training) skews and data leakage are common. Although the machine learning community has extensively discussed the need for feature stores and their purpose, this paper aims to capture the core architectural components that make up a managed feature store and to share the design learning in building such a system.Comment: All the authors are from the AzureML Feature Store product group and are listed in alphabetical order. Bhala Ranganathan: System architect and tech lead of AzureML Feature Store. Feng Pan, Qianjun Xu: Engineering managers. Sethu Raman: Product Manager of AzureML Feature Store who structured and organized the product vision and specification

    Development and validation of a novel necroptosis-related gene signature for predicting prognosis and therapeutic response in Ewing sarcoma

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    Ewing sarcoma (ES) is the second most common malignant bone tumor in children and has a poor prognosis due to early metastasis and easy recurrence. Necroptosis is a newly discovered cell death method, and its critical role in tumor immunity and therapy has attracted widespread attention. Thus, the emergence of necroptosis may provide bright prospects for the treatment of ES and deserves our further study. Here, based on the random forest algorithm, we identified 6 key necroptosis-related genes (NRGs) and used them to construct an NRG signature with excellent predictive performance. Subsequent analysis showed that NRGs were closely associated with ES tumor immunity, and the signature was also good at predicting immunotherapy and chemotherapy response. Next, a comprehensive analysis of key genes showed that RIPK1, JAK1, and CHMP7 were potential therapeutic targets. The Cancer Dependency Map (DepMap) results showed that CHMP7 is associated with ES cell growth, and the Gene Set Cancer Analysis (GSCALite) results revealed that the JAK1 mutation frequency was the highest. The expression of 3 genes was all negatively correlated with methylation and positively with copy number variation (CNV). Finally, an accurate nomogram was constructed with this signature and clinical traits. In short, this study constructed an accurate prognostic signature and identified 3 novel therapeutic targets against ES

    East European Journal Of Psycholinguistics

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    East European Journal of Psycholinguistics is an international double-blind peerreviewed academic periodical published semiannually. The aim of the journal is to provide a forum for scholars to share, foster, and discuss globally various new topics and advances in different fields of modern psycholinguistics. The journal publishes original manuscripts covering but not limited to the following theoretical and applied fields of psycholinguistics: Bilingualism Clinical Psycholinguistics Cognitive Linguistics Cognitive Psychology Discourse Analysis Forensic Linguistics First and Second/Foreign Language Acquisition Neurolinguistics Pragmatics Psychology of Language and Speech Sociolinguistics Translation Studie

    Exploring the Relationship between Chinese First Year University Students’ Beliefs about Language Learning and Foreign Language Anxiety

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    The aims of the study are to investigate what beliefs Chinese university first-year English majors have about language learning, whether they report anxiety about studying English, and whether there is a relationship between their beliefs and language anxiety. Two questionnaires were used in this study – Tanaka’s beliefs questionnaire and Horwitz’s Foreign Language Classroom Anxiety Scale. A series of statistical analyses were carried out on the responses. The results revealed that the Chinese university first-year English majors held four types of beliefs, namely Approach to Learning English, Self-efficacy and Confidence in English, Formal and Structured Learning, and Ease of Learning English. Comparing the means of all items in the beliefs questionnaire, it seemed that the respondents held a strong belief in the importance of learning vocabulary for them to speak English well. The respondents also reported some anxiety about learning English. However, it was interesting that the overall mean of their anxiety scores was lower than the means in previous studies. This study also found that there was no significant relationship between the participants’ beliefs and their language anxiety, which echoed the results of Kunt’s (1997) study, but two beliefs factors and several items were found to weakly correlate with the anxiety.

    Systematic Evaluation of the Effect of Rehabilitation of Lower Limb Function in Children with Cerebral Palsy Based on Virtual Reality Technology

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    As times go by, people’s standard of living is constantly improving, but the medical pressure exerted by children with cerebral palsy is also increasing and the recovery of lower limb function in children with cerebral palsy after treatment has also gets people’s attention. Of course, the relevant medical equipment is constantly improving, especially the appearance of virtual reality technology, which has played an extremely important role in restoring the lower extremities of children with cerebral palsy. In order to study the role that virtual reality technology can play in children with cerebral palsy, this article collects relevant information, builds a case template, and uses comprehensive quantification by investigating patients, examining relevant documents, and interviewing professionals. With qualitative analysis, a damage assessment matrix is created. Experimental results prove that the use of virtual reality technology can improve the treatment efficiency of children with cerebral palsy by more than 30%. In terms of the rehabilitation effect of children’s lower limb function, virtual reality technology is more targeted for the treatment of children with far-reaching effects. It is much higher than traditional treatment methods, and the mobility of the children’s lower limbs is restored by more than 80%. This shows that virtual reality technology can play an important role in the rehabilitation of the lower limbs of children with cerebral palsy

    Data_Sheet_1_Development and validation of a novel necroptosis-related gene signature for predicting prognosis and therapeutic response in Ewing sarcoma.zip

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    Ewing sarcoma (ES) is the second most common malignant bone tumor in children and has a poor prognosis due to early metastasis and easy recurrence. Necroptosis is a newly discovered cell death method, and its critical role in tumor immunity and therapy has attracted widespread attention. Thus, the emergence of necroptosis may provide bright prospects for the treatment of ES and deserves our further study. Here, based on the random forest algorithm, we identified 6 key necroptosis-related genes (NRGs) and used them to construct an NRG signature with excellent predictive performance. Subsequent analysis showed that NRGs were closely associated with ES tumor immunity, and the signature was also good at predicting immunotherapy and chemotherapy response. Next, a comprehensive analysis of key genes showed that RIPK1, JAK1, and CHMP7 were potential therapeutic targets. The Cancer Dependency Map (DepMap) results showed that CHMP7 is associated with ES cell growth, and the Gene Set Cancer Analysis (GSCALite) results revealed that the JAK1 mutation frequency was the highest. The expression of 3 genes was all negatively correlated with methylation and positively with copy number variation (CNV). Finally, an accurate nomogram was constructed with this signature and clinical traits. In short, this study constructed an accurate prognostic signature and identified 3 novel therapeutic targets against ES.</p
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